Table 2.
Measurement | Description | Source | Groups Measured | Timinga |
---|---|---|---|---|
Primary health endpoints |
Blood pressure (brachial systolic and diastolic) C-reactive protein (systemic inflammation) Glycated hemoglobin (HbA1c) |
SphygmoCor XCEL monitor Dried blood spots Finger-stick point-of-care instrument |
All participants All participants All participants |
All 6 visits, day 2 All 6 visits, day 2 All 6 visits, day 2 |
Secondary health endpoints |
Other biomarkers of systemic injury and inflammation Metabolomics Augmentation index and central pulse pressure Blood lipids (LDL, HDL, total cholesterol, triglycerides) Self-reported health symptoms Fractional exhaled nitric oxide (airway inflammation) Telomere length from buccal cells |
Dried blood spots Dried blood spots SphygmoCor XCEL Finger-stick point-of-care instrument Questionnaires NIOX Vero and Aero monitors Buccal scrapes |
All participants All participants All participants All participants All participants Sub-set of participants Sub-set of participants |
All 6 visits, day 2 Visit 1 All 6 visits, day 2 All 6 visits, day 2 All 6 visits, day 2 All 6 visits, day 2 Visits 1-4, day 2 |
Exposure assessments | Assigned stove type | Randomization | All participants | See Table 1 scheme |
Kitchen | ||||
PM2.5 Black carbon Ultrafine PM Real time and gravimetric PM2.5 Carbon monoxide |
Triplex cyclone and AirChek pump PM2.5 Filters and Sootscan Discmini Personal Data Ram Dräger Pac 7000 |
All kitchens All kitchens Sub-set of kitchens Sub-set of kitchens All kitchens |
All 6 visits, 24-hours All 6 visits, 24-hours Visits 1-4, 24-hours Visits 1-4, 24-hours Visits 1-3, 24-hours |
|
Personal | ||||
PM2.5 Black carbon Compliance with wearing monitors Carbon monoxide |
Triplex cyclone and AirChek pump, UPAS PM2.5 Filters and Sootscan Accelerometer Dräger Pac 7000 |
All participants All participants All participants All participants |
All 6 visits, 24-hours All 6 visits, 24-hours All 6 visits, 24-hours Visits 1-3, 24-hours |
|
Other sources of household air pollution |
Neighbors, traffic, trash burning, kerosene use Smoking status (cigarettes and puro) Secondhand smoke exposure |
Questionnaires Questionnaires Screening |
All participants All participants All participants |
All 6 visits, day 1 Screening and all 6 visits, day 2 Screening |
Stove use |
Self-reported use of all cookstoves, behaviors Electronic monitoring of cookstove temperature Justa cookstove maintenance, changes, preferences Time cooking separately for animals |
Questionnaires Stove Use Monitors (SUMs) Questionnaires Questionnaires |
All participants All cookstoves Justa recipients All participants |
All 6 visits, day 2 All 6 visits, 24-hours Visits 3-6, day 2 All 6 visits, day 2 |
Household and kitchen characteristics |
Elevation and GPS coordinates Kitchen temperature and humidity Kitchen ventilation/openings Kitchen location, size, and housing materials |
Maps.me on smart phones EasyLog monitor Questionnaires Questionnaires |
All households All kitchens All kitchens All kitchens |
Visit 1 (repeated if new house) All 6 visits, 24-hours Visit 1 (repeated if new house) Visit 1 (repeated if new house) |
Socioeconomic and demographics |
Income sources Material items, electricity, education, beds, age Household size, age of youngest child |
Questionnaires Questionnaires Questionnaires |
All participants All participants All participants |
All 6 visits, day 1 Visit 1, day 1 All 6 visits, day 1 |
Other health-related measures |
Illnesses, previous diagnoses Medication and vitamin use 24-hour dietary recall and diversity Weekly physical activity Body mass index (BMI), waist and hip circumference Pregnancy |
Questionnaires Questionnaires Questionnaires Questionnaires Anthropometric measures Screening and Questionnaires |
All participants All participants All participants All participants All participants All participants |
All 6 visits, day 2 All 6 visits, day 2 All 6 visits, day 2 All 6 visits, day 2 All 6 visits, day 2 Screening and all 6 visits, day 1 |
aWomen received six repeated measures over the 3-year study period, with approximately six months between visits. Each study visit included two consecutive days of data collection: day 1 set-up of all exposure monitors, and day 2 take-down of monitors and collection of health measures. Further details on timing and collection procedures can be found in the “Study visits” section