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. 2019 Jul 2;10:1479. doi: 10.3389/fimmu.2019.01479

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Copyright © 2019 Kiernan, Wang, Vanderplow, Cherukuri, Cahill and Watters.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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RNA-seq analyses of neonatal male and female microglia. (A) Heatmap of z-scores (left) and MDS analysis (right) for normalized gene expression in male and female microglia in basal conditions. (B) Heatmap (left) and MDS analysis (right) of normalized gene expression in male and female microglia in inflammatory (LPS) conditions. (C) Gene ontology for genes upregulated in males relative to females in basal (left) and inflammatory (right) conditions. (D) The top-ranking match for Homer motif analysis of the 8 genes identified in the GO category “cognition”.