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. 2019 Jul 8;17:217. doi: 10.1186/s12967-019-1964-6

Table 2.

Results of univariate and multivariate Cox regression of overall survival in the training cohort

Cohort Training cohort
Variable Univariate Multivariate
HR 95% CI P-value HR 95% CI P-value
Immune infiltrating score 6.459 4.409–9.462 < 0.001 5.322 3.574–7.926 < 0.001
Age 1.025 1.014–1.035 < 0.001 1.024 1.014–1.035 < 0.001
Sex 0.031 0.079
 Female Reference Reference
 Male 1.245 1.021–1.518 0.031 1.196 0.979–1.460 0.079
TNM stage < 0.001 < 0.001
 Stage I Reference Reference
 Stage II–III 2.682 2.195–3.278 < 0.001 2.443 1.996–2.990 < 0.001
 Stage IV 2.256 0.721–7.053 0.162 1.835 0.586–5.740 0.297

HR hazard ratio, CI confidence interval