Table 2.
Basic characteristics and treatment results for patients with abscess diameter ≥ 40 mm and for matched patients
| Abscess ≥ 40 mm | Antibiotics (n = 79) | Drainage (n = 20) | p value | Matched antibiotics (n = 18) | Matched drainage (n = 18) | p value |
|---|---|---|---|---|---|---|
| Basic characteristics | ||||||
| Sex female | 50 (63%) | 8 (40%) | 0.06a | 11 (61%) | 7 (39%) | 0.18a |
| Age, years, median (IQR) | 61 (52–73) | 60 (48–69) | 0.52b | 67 (55–78) | 60 (50–69) | 0.15b |
| WBC, × 109/l, median (IQR) | 13.6 (10.1–15.6) | 11.1 (8.5–13.9) | 0.10b | 12.0 (9.2–15.3) | 10.5 (8.4–13.1) | 0.26b |
| CRP, mg/l, median (IQR) | 140 (97–231) | 126 (44–277) | 0.79b | 162 (50–235) | 110 (39–270) | 0.45b |
| Any earlier diverticulitis | 20 (25%) | 8 (40%) | 0.19a | 6 (33%) | 8 (44%) | 0.49a |
| Multiple abscesses | 15 (19%) | 2 (10%) | 0.51c | 1 (6%) | 2 (11%) | 1c |
| Abscess size, mm, median (IQR) | 51 (44–66) | 60 (52–88) | 0.007b | 58 (50–66) | 58 (50–67) | 0.95b |
| Charlson Comobidity Index, median (IQR) | 2 (1–4) | 2 (1–4) | 0.94b | 3 (1–6) | 2 (1–4) | 0.25b |
| Corticosteroid medication | 11 (14%) | 4 (20%) | 0.5c | 5 (28%) | 4 (22%) | 1c |
| Outcomes | ||||||
| Overall failure | 21 (27%) | 7 (35%) | 0.46a | 8 (44%) | 6 (33%) | 0.49a |
| 30-day mortality | 4 (5%) | 1 (5%) | 1c | 1 (6%) | 1 (6%) | 1c |
| Need of emergency surgery during initial admission or within 30 days | 13 (17%) | 6 (30%) | 0.21c | 5 (28%) | 5 (28%) | 1a |
| Readmission within 30 days of discharge | 6 (14%) | 2 (10%) | 0.66c | 3 (17%) | 2 (11%) | 1c |
| Recurrence of diverticulitis during follow-upd | 20 (32%), n = 62e | 1 (8%), n = 13e | 0.1c | 2 (17%), n = 12e | 1 (8%), n = 12e | 1c |
| Complicated recurrenced | 13 (21%), n = 62e | 1 (8%), n = 13e | 0.44c | 1 (8%), n = 12e | 1 (8%), n = 12e | 1c |
| Sigma resection later than 30 days after discharged | 29 (47%), n = 62e | 9 (69%), n = 13e | 0.14a | 8 (44%), n = 12e | 9 (50%), n = 12e | 1c |
| Temporary stoma | 4 (5%) | 1 (5%) | 1c | 2 (17%), n = 12e | 1 (8%), n = 12e | 1c |
| Permanent stoma | 4 (5%) | 1 (5%) | 1c | 1 (8%), n = 12e | 1 (8%), n = 12e | 1c |
| Hospital stay, days, median (IQR) | 4 (3–8) | 7 (3–13) | 0.17b | 6 (3–10) | 6 (3–12) | 0.73b |
WBC white blood cell count, IQR interquartile range, CRP C-reactive protein
aχ2 test
bMann-Whitney U test
cFisher’s exact test
dMedian follow-up 71 months (IQR 46–100 months) for all patients
ePatients who died within 30 days or had emergency surgery during initial admission or within 30 days were removed from the total