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The most reported and high risk genes among Iranian BC patients
| Gene | Number of studies | Number of patients (total) | Number of controls (total) |
|---|---|---|---|
| CYP2D6 | 2 | 185 | – |
| FOXP3 | 2 | 95 | 80 |
| LEPTIN | 2 | 303 | 271 |
| TGFβ | 2 | 210 | 210 |
| HER2 | 3 | 509 | 15 |
| ERBB4 | 3 | 490 | 486 |
| CASP8 | 2 | 263 | 203 |
| P53 | 2 | 467 | 203 |
| PTEN | 3 | 260 | 70 |
| VDR | 3 | 477 | 497 |
| ATM | 3 | 298 | 248 |
| BRCA1 | 3 | 259 | – |
| MTHFR | 2 | 378 | 306 |
| DNMT3 | 2 | 172 | 138 |
| ERα | 2 | 169 | 157 |
