. 2019 Jul 2;10:1503. doi: 10.3389/fmicb.2019.01503

TABLE 1.

Ratios of relative ARGs abundances in kits and in the three donor does.

		ARG ratio of kits vs. control kits (n = 37 litters, one kit per litter)							ARG ratio of donor does vs. lactating dams (n = 37)
	ARG	ControlNF/ Control	I41/ Control	P41/ Control	I43/ Control	P43/ Control	I44/ Control	P44/ Control	donor Doe41/Lactating Dams	donor Doe43/Lactating Dams	donor Doe44/Lactating Dams
Aminoglycoside	aac6Im				0.38			0.4	0.47	0.16	0.11
	aacA.aphD								0.15	0.00	0.01
	aadE				0.45	0.49			0.57	0.29	0.51
	ant6Ib					0.42			0.44	0.23	0.16
	aph2Ib				0.40	0.28		0.4	0.51	0.06	0.13
	aph3Ib								2.10	0.05	0.02
	aphA3				0.49	0.32			0.44	0.31	0.31
	MGaph								0.03	0.02	0.00
	strB								2.40	0.02	0.00
Beta lactam	CblA1				0.04			0.04	0.11	0.19	0.04
	cepA29								2.25	0.26	0.01
Macrolide	ermB				0.47	0.19			0.43	0.09	0.03
	ermG				0.21	0.11	0.5		0.18	0.08	0.13
	lnuC								1.01	0.38	0.12
	mefA		311						15.70	1.05	0.01
Phenicol	floR								1.73	2.46	0.15
Sulfamide	sul2								48.50	0.00	0.00
Tetracycline	tet32		1.7						0.46	0.31	1.10
	tet33				9.20			11.8	4.82	1.31	0.08
	tet40_1				0.45	0.32			0.63	0.44	0.27
	tetM								0.84	0.15	0.70
	tetO								0.35	0.86	0.18
	tetQ								0.32	0.63	0.37
	tetY								0.00	0.00	0.00
Trimethoprim	dfrD								0.88	0.00	0.00
Vancomycin	vanTG								0.84	1.34	2.27
Significance of	p-values	0.62	0.5	0.2	0.08	0.02^*	0.2	0.02^*
separation of the communities from the controls based on 16S data	R²	0.12	0.10	0.14	0.13	0.16	0.12	0.16

The kits are compared to the kits of the control group at weaning. The donor does are compared to the lactating dams. The value of ARGs in the donor does was highlighted when it was lower than the ARG abundance in the lactating dams. The ratios are reported only when the kits exposed to the microbial communities were significantly different from the control kits. The ratios higher than 1 are in red (see Supplementary Table S3 for values before ratio). The pairwise p-values of the group separation of the microbial communities from the controls based on 16S rRNA sequences are also reported. ^*Indicates statistical significance.