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. 2019 May 14;14(10):1343–1365. doi: 10.2217/nnm-2018-0347

Figure 1. . The nanoscale metal-organic frameworks as drugs and genes carriers.

Figure 1. 

(A) The structures of MIL-100, UiO-66, MIL-127 and MIL-53 and caffeine molecule. (B) Caffeine release profiles from different porous metal-organic frameworks in PBS solution at 37°C. (C) Schematic presentation of siRNA/UiO-cisplatin synthesis and prodrug loading. (D) Cytotoxicity results of the SKOV-3 cells incubated with different samples showing the resensitization effect with siRNA/UiO-cisplatin nanoparticles.

MIL: Materials of Institute Lavoisier; UiO: Universitetet i Oslo.

(A) Reproduced with permission from [33] © American Chemical Society (2013).

(B) Reproduced with permission from [33] © American Chemical Society (2013).

(C) Reproduced with permission from [34] © American Chemical Society licensed with Standard ACS Author Choice/Editors’ Choice usage agreement (2014).

(D) Reproduced with permission from [34] © American Chemical Society licensed with Standard ACS Author Choice/Editors’ Choice usage agreement (2014).

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