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. 2019 May 14;14(10):1343–1365. doi: 10.2217/nnm-2018-0347

Figure 8. . The porphyrinic metal-organic frameworks and metal-organic framework-based nanomaterials for photodynamic therapy.

Figure 8. 

(A) Scheme of using Fe-TBP MOFs to overcome hypoxia for PDT-primed cancer immunotherapy. (B) Time-dependent oxygen generation. (C) Tumor growth curves of CT26 tumor-bearing mice with T-cell or B-cell depletion. (D) Scheme of the core-satellite MOF-UCNPs assemblies and the mixture of the MOF-UCNPs. (E) Singlet-oxygen production from the MOF-UCNPs with different ratios.

MOF: Metal-organic framework; NIR: Near infrared; PDT: Photodynamic therapy; TBP: 5,10,15,20-tetra(p-benzoato)porphyrin; UCNP: Upconversion nanoparticle.

(A) Reproduced with permission from [103] © American Chemical Society (2018).

(B) Reproduced with permission from [103] © American Chemical Society (2018).

(C) Reproduced with permission from [103] © American Chemical Society (2018).

(D) Reproduced with permission from [109] © WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim (2017).

(E) Reproduced with permission from [109] © WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim (2017).