FIGURE 4.

Histological evaluation of vaginal damage and inflammatory levels. (A) Mice in the prevention group were injected with estrogen and then 0.77, 1.54, 3.08 mg/kg PAE or 20 mg/kg FCZ was given as a preventative treatment 2 days prior to the mice being infected vaginally with C. albicans. Five days later, the tissues were harvested and sectioned for HE staining. The results were observed under 10× and 40× magnification. The little blue and purple dots indicate PMNs. (B) Mice in the treatment group were treated with estrogen and then infected vaginally with C. albicans. The infected mice were then treated with 0.77, 1.54, 3.08 mg/kg PAE or 20 mg/kg FCZ. After 5 days, the tissues were harvested and sectioned for HE staining. The results were observed under 10 × and 40× magnification. The little blue and purple dots indicate PMNs.