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. 2019 Jul 1;32(3):160–167. doi: 10.3344/kjp.2019.32.3.160

Table 3.

Effect of GABAA Antagonist Bicuculline on Artemisinin Anti-Nociception in the Acetic Acid-Induced Writhing Test in Mice (n = 6)

Treatment Dose (mg/kg, i.p.) Writhing count (mean ± SEM) Inhibition (%)
Artemisinin 10 32.17 ± 2.14 63.08
Bicuculline 2 78.52 ± 9.45* 0*
Bicuculline + artemisinin 2 + 10 54.37 ± 6.13* 26.70*

i.p.: intraperitoneal, SEM: standard error of mean.

*

P < 0.0001 vs. artemisinin.