Table 3.
Most frequent events (occurring in ≥ 10% patients) | Cohort 1(%) n =12 |
Phase II (%) n = 35a |
All n = 41) |
---|---|---|---|
Hypoalbuminemia | 12 (100) | 32 (91) | 38 (93) |
Anemia | 12 (100) | 32 (91) | 38 (93) |
Alkaline phosphatase increased | 12 (100) | 31 (89) | 37 (88) |
Thrombocytopenia | 10 (83) | 30 (86) | 36 (88) |
Aspartate aminotransferase increased | 7 (57) | 28 (80) | 31 (76) |
Rash acneiform | 8 (67) | 19 (54) | 27 (66) |