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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: J Hepatol. 2018 May 25;69(4):886–895. doi: 10.1016/j.jhep.2018.05.021

Figure 2.

Figure 2

Inflammatory responses in EtOH-induced liver injury. WT and IEhif1α−/− mice were pair- or alcohol-fed for 24 days. (A) Chloroacetate esterase (CAE) localization (cell-localized fuchsia staining) in livers. Original magnification, ×10. Arrows indicate neutrophil infiltration. (B) F4/80 staining of the liver tissues. DAPI (blue) was used to counterstain nuclei. Original magnification, ×10. (C, D, E) Hepatic gene expression of proinflammatory cytokines TNF-α, IL-6 and chemokine MCP-1, respectively. (F) Serum alanine aminotransferase (ALT) activities. Data are expressed as mean ± SEM. AF, alcohol-fed; PF, pair-fed.