Skip to main content
. Author manuscript; available in PMC: 2019 Jul 9.
Published in final edited form as: Chem Rev. 2018 Oct 18;118(22):11194–11258. doi: 10.1021/acs.chemrev.8b00369

Figure 14.

Figure 14

Interaction map for the catalytic site of TvNH with contacts to the catalytic site Ca2+ and inosine as a catalytic site ligand. Asp10Ala mutant prevented hydrolysis of the inosine. Trp83 and Trp260 are stacked with the leaving group. Reproduced with permission from ref 94. Copyright 2006 Elsevier.