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. Author manuscript; available in PMC: 2019 Jul 9.
Published in final edited form as: Chem Rev. 2018 Oct 18;118(22):11194–11258. doi: 10.1021/acs.chemrev.8b00369

Figure 34.

Figure 34

Inhibition constants (nM) for potential transition state analogues of P. falciparum (blue) and human (red) OPRT enzymes. Reproduced with permission from ref 222. Copyright 2013 American Society for Biochemistry and Molecular Biology.