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. Author manuscript; available in PMC: 2019 Jul 9.
Published in final edited form as: Chem Rev. 2018 Oct 18;118(22):11194–11258. doi: 10.1021/acs.chemrev.8b00369

Figure 50.

Figure 50

Thermodynamic profiles of ΔH, –TΔS, and ΔG for the binding of first-and second-generation inhibitors to the first active site of E. coli MTAN, S. enterica MTAN, and V. cholera MTAN. Reproduced from ref 292. Copyright 2012 American Chemical Society.