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MTAN from H. pylori bound to R = butyl for the 1-substituted 2-aminopropanol adducts of 9-deazaadenine. (Left) Electron density of 1RMSD for the bound ligand. For maps calculated with 2Fobs – Fcalc coefficients. (Right) Surface representation of the MTAN protein surface showing the buried 9-deazaadenine and the hydrophobic channel leading to the solvent. PDB entry 4YO8. Reproduced from ref 324. Copyright 2015 American Chemical Society.
