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. Author manuscript; available in PMC: 2019 Jul 9.
Published in final edited form as: Chem Rev. 2018 Oct 18;118(22):11194–11258. doi: 10.1021/acs.chemrev.8b00369

Figure 59.

Figure 59

Intrinsic KIE values for the arsenolysis of inosine by bovine and human PNPs. Each KIE shown here was measured in independent experiments with an inosine molecule isotopically labeled in the indicated positions.350,351