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. Author manuscript; available in PMC: 2019 Jul 9.
Published in final edited form as: Chem Rev. 2018 Oct 18;118(22):11194–11258. doi: 10.1021/acs.chemrev.8b00369

Figure 71.

Figure 71

Dissociation constants for human PNP comparing cyclic with acyclic Immucillins. Compounds marked with an asterisk exhibited slow-onset inhibition kinetics. Values are equilibrium dissociation constants in pM. Source of Ki values. Reproduced from ref 387. Copyright 2009 American Chemical Society.