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. Author manuscript; available in PMC: 2019 Jul 9.
Published in final edited form as: Chem Rev. 2018 Oct 18;118(22):11194–11258. doi: 10.1021/acs.chemrev.8b00369

Figure 85.

Figure 85

Marburg virus infections in cynomolgus macaques treated with BCX4430 (ImmA; Tx). Animals (n = 6) in each group were infected with virus on day 0. BCX4430 (15 mg/kg) was given twice a day by i.m. injection starting at 1, 24, or 48 h after exposure to the virus. Vehicle indicates no BCX4430 was given. Reproduced with permission from ref 446. Copyright 2014 Nature Publishing.