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Schematic illustration of development of fine-scale networks and individual synaptic connections. The development of excitatory synaptic connections from L4 cells to L2/3 pyramidal cells during the period from eye opening (left) to 2 weeks after eye opening is shown schematically for rats reared normally (top right), in darkness (middle right), and with binocular deprivation (bottom right). The thickness of lines indicates the strength of synaptic connections.
