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. 2019 May 16;14(8):804–817. doi: 10.1080/15592294.2019.1615358

Figure 3.

Figure 3.

The effect of FA on the promoter methylation of DNMT1, DNMT3A, and DNMT3B in HepG2 cells. DNA isolated from control and FA-treated HepG2 cells were assayed for DNMT promoter methylation using the OneStep qMethyl Kit. Fusaric acid induced promoter hypermethylation of DNMT1 and DNMT3B, and altered promoter methylation of DNMT3A in HepG2 cells. Results are represented as mean fold-change ± SD (n = 3). Statistical significance was determined by one-way ANOVA with the Bonferroni multiple comparisons test (***p < 0.0001).