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. 2019 May 27;14(8):741–750. doi: 10.1080/15592294.2019.1615355

Table 1.

Disease-specific survival analysis in 75 breast cancer patients.

  Univariate analysis
(N = 73/75 cases)
Multivariate analysis
Parameters HR (CI 95%) p HR (CI 95%) p
Age (years)
≤55
>55
1.0
5.658
(0.654–48.949)
0.1154    
Clinical stage
I, IIA, IIB
IIIA, IIIB
1.0
23.301
(2.589–209.744)
0.0050    
Tumour size (mm)
≤20
>20
1.0
nd
0.9950    
Lymph nodes involvement
≤4
>4
1.0
14.271
(1.632–124.788)
0.0163    
Metastasis
Presence
Absence
1.0
18.792
(3.093−114.186)
0.0014 1.0
18.792
(3.093−114.186)
0.0014
Histological grade
I, II
III
1.0
1.230
(0.248–6.111)
0.8001    
ER
Positive
Negative
1.0
4.288
(0.768–23.939)
0.0971    
PgR
Positive
Negative
1.0
nd
0.9959    
Her-2
Negative
Positive
1.0
1.506
(0.167–13.590)
0.7151    
p53
Negative
Positive
1.0
0.568
(0.062–5.213)
0.6169    
Proliferative index (Ki-67)
Low (≤25%)
High (>25%)
1.0
0.640
(0.117–3.508)
0.6069    

HR: Hazard Ratio; CI: Confidence Interval; N: Number of cases; nd: not determined; in bold: p-value <0,05.