Table 3. Bayesian MCMC estimates based on modes of the posterior distributions and 95% credible intervals for mutation effect (e) and mutation frequency (q) parameters under two- or three-category models along with BIC relative to the model with two categories of mutation effects.
Parameter estimate (95% credible interval) | |||||
---|---|---|---|---|---|
Model (no. mutation categories) | e1 | q1 | e2 | q2 | BIC |
2 | −0.031 (−0.044, −0.023) | 0.042 (0.020, 0.079) | - | - | 0 |
3 | −0.024 (−0.043, −0.011) | 0.071 (0.031, 0.42) | 0.021 (0.010, 0.068) | 0.048 (0.010, 0.41) | −147 |
Abbreviations: BIC, Bayesian information criterion; MCMC, Markov chain Monte Carlo.