Table 5. Average squared effects of mutations (×1,000) of certain mutation type classifications (S1 Data) estimated under the two-sided gamma distribution model.

For example, in the row labelled ‘SNP versus Indel’, e²(−) and e²(+) are the average squared effects for SNP and indel mutations, respectively. P values for the difference between the squared effects of mutations were obtained by bootstrapping mutations 1,000 times.

Mutation type	e2(−)	e2(+)	P value
SNP versus indel	0.074	0.073	0.84
Nonexonic versus exonic	0.061	0.083	0.15
Nonintronic versus intronic	0.081	0.059	0.17
Nonintergenic versus intergenic	0.074	0.067	0.92