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Interaction of Loop1 in the TdT chimera with the downstream dsDNA substrate. A, Loop1 conformation in the TdT-μ chimera–downstream dsDNA ternary complex. The dNTP and the templating base are represented in stick form. B, interaction between the N-terminal part of Loop1 and TdT. C, interaction between the middle part of Loop1 and TdT. D, interaction between the α helix of Loop1 and TdT.
