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. 2019 May 29;294(27):10392–10406. doi: 10.1074/jbc.RA119.007743

Figure 7.

Figure 7.

Motor behavior of mice following unilateral striatal injections of different α-synuclein species. C57BL/6J mice received unilateral striatal injections of 2 μl of monomer (300 μm), F-L (150 μm), F-M (150 μm), F-S (150 μm), and O (300 μm). Three months later, mice were subjected to the following behavior tests: open field, pole test, cage hang, and cylinder test (modified for mice). Numbers of mice for pole test, cage hang, and open field are as follows: monomer (12); F-L (11); F-M (12); F-S (11); and O (15). Numbers of mice for cylinder test are as follows: monomer (10); F-L (10); F-M (10); F-S (10); and O (10). The data were analyzed by one-way ANOVA: pole test F(4,69) = 4.7, p = 0.002; cage hang F(4,66) = 2.86, p = 0.03; open field/% time center F(4,69) = 1,1, p = not significant; open field/velocity F(4,69) = 0.6, p = not significant; hind limb steps F(4,45) = 1.1, p = not significant; rearing F(4,45) = 0.5, p = not significant. *, p < 0.05.