Figure 2.
Diagram of the rDNA repeats and surrounding sequence, as assembled for cosmids YSCL9634 (left, GenBank accession no. U53879) and YSCL9362 (right, GenBank accession no. U51921). The numbers shown are the nucleotide coordinates for cosmid YSCL9634. The left rDNA junction (U53879 coordinate 21,811) begins at nucleotide 451,418 of chromosome XII; the right rDNA junction (U53879 coordinate 39,322) is at nucleotide 468,929. The sequence includes 1.92 rDNA repeats, representing the leftmost and rightmost copies in the genome. The remaining 100–200 rDNA repeats in the genome are represented as an insertion at coordinate 30,947. Only one complete 5S rDNA gene (in the left rDNA repeat) is included in this sequence (nucleotides 30,069–30,189); the 5S rDNA genes in the 3.6-kb repeats are variant genes. The 5S rDNA gene in the last rDNA repeat (nucleotides 39,204–39322) includes all 5′ non-translated sequences (like the normal 5S rDNA in the first repeat), but is missing sequences downstream of the 5S rRNA transcript (like the 5S rDNA genes in the 3.6-kb repeats).