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. 2019 Jul 5;11:6229–6244. doi: 10.2147/CMAR.S189661

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© 2019 Ravegnini et al.

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miRNAs profile .

Notes: (A) miRNA hierarchical clustering. miRNAs identified as differentially expressed between BYL719-sensitive and -resistant GIST cell lines were selected as markers for unsupervised hierarchical clustering. (B) GO functional enrichment analysis of up- and downregulated miRNAs. (C) Main miRNAs involved in cancer (blue), AKT–mTOR (green) and JAK signaling cascades (pink) pathways.