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. 2019 Jul 5;11:6229–6244. doi: 10.2147/CMAR.S189661

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© 2019 Ravegnini et al.

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Global methylation profile.

Notes: (A) Box plots showing the β-values of CpGs islands at promoters only . General hypermethylation was more common in the BYL719-resistant cell lines. (B, C) Scatterplots of genome-wide DNA methylation levels (β). To highlight general hypermethylation, CpG islands with Δβ<–0.2 or >0.2 are shown.