Table 2.
Univariate analyses of predictors of mechanical ventilator use among 10,173 U.S. children hospitalized with seasonal influenza.
| n (%) | OR (95% CI) | P | |
|---|---|---|---|
| Gender | 0.72 | ||
| Male (N=5,760) | 527 (9.2) | Reference | |
| Female (N=4,413) | 413 (9.4) | 1.02 (0.90 – 1.17) | |
| Age | <0.001 | ||
| <2 months (N=1,412) | 97 (6.9) | Reference | |
| 2–11 months (N=2,317) | 264 (11) | 1.74 (1.37 – 2.22) | |
| 1–4 years (N=3,252) | 287 (8.8) | 1.31 (1.03 – 1.67) | |
| 5–11 years (N=2,133) | 184 (8.6) | 1.28 (0.99 – 1.65) | |
| 12–17 years (N=1,059) | 108 (10) | 1.54 (1.16 – 2.05) | |
| Race | <0.001 | ||
| White (N=6,393) | 585 (9.2) | Reference | |
| Black (N=2,573) | 191 (7.4) | 0.80 (0.67 – 0.94) | |
| Non-White/non-Black (N=1,207) | 164 (14) | 1.56 (1.30 – 1.88) | |
| Primary payer | 0.70 | ||
| Private (N=2,620) | 247 (9.4) | Reference | |
| Non-Private (N=7,553) | 693 (9.2) | 0.97 (0.83 – 1.13) | |
| Season | 0.28 | ||
| 2006 – 07 (N=2,870) | 280 (9.8) | Reference | |
| 2007 – 08 (N=4,336) | 378 (8.7) | 0.88 (0.75 – 1.04) | |
| 2008 – 09 (N=2,967) | 282 (9.5) | 0.97 (0.82 – 1.16) | |
| Health status | |||
| Previously healthy (N=4,415) | 205 (4.6) | Reference | |
| Non-ACIP condition a (N=713) | 92 (13) | 3.04 (2.35 – 3.94) | <0.001 |
| ACIP-defined condition b | |||
| Cardiovascular disease (N=650) | 158 (24) | 3.59 (2.96 – 4.36) | <0.001 |
| Neurological disease (N=1,425) | 334 (23) | 4.11 (3.55 – 4.77) | <0.001 |
| Chronic lung disease (N=899) | 195 (22) | 3.17 (2.66 – 3.78) | <0.001 |
| Immunosuppression (N=1,008) | 97 (9.6) | 1.05 (0.84 – 1.31) | 0.66 |
| Metabolic disease (N=343) | 48 (14) | 1.63 (1.19 – 2.23) | 0.002 |
| Renal disease (N=109) | 13 (12) | 1.34 (0.74 – 2.39) | 0.33 |
| Hepatic disease (N=82) | 21 (26) | 3.44 (2.09 – 5.67) | <0.001 |
| Hematologic disease (N=410) | 3 (0.7) | 0.07 (0.02 – 0.22) | <0.001 |
| Asthma (N=1,861) | 135 (7.2) | 0.73 (0.60 – 0.88) | 0.001 |
| Chronic aspirin therapy (N=23) | 0 | ||
| Bacterial pneumonia (N=567) | 199 (35) | 6.47 (5.36 – 7.81) | <0.001 |
a
Compared to previously healthy children.
b
Compared to children without each risk factor.