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. 2019 Jul 3;6(2):e001048. doi: 10.1136/openhrt-2019-001048

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© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Distribution of bio-ADM according to signs of peripheral oedema within each centre. HARVEST-Malmö n=301, 215 events (p<0.001), GREAT Network Rome n=208, 123 events (p=0.080). bio-ADM, bioactive adrenomedullin, HARVEST, HeArt and bRain failure inVESTigation trial.