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. 2019 Jun 14;55(2):391–404. doi: 10.3892/ijo.2019.4825

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Copyright: © Owusu-Ansah et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Established BxPC-M8 cell line demonstrates different morphology but a similar growth pattern compared with BxPC-3. (A) Schematic representation of the establishment of BxPC-M8 cells from the parent cell line BxPC-3. (B) Images of BxPC-3 and BxPC-M8 stained with Giemsa (magnification, x200); epithelial-mesenchymal transition phenotype with the green arrows. (C and D) Growth curve indicated a similar growth rate between the two cell lines. (E and F) Sensitivity to gemcitabine revealed no significant difference between BxPC-3 and BxPC-M8 cells as demonstrated by the IC₅₀ value. n.s., not significant; IC₅₀, half-maximal inhibitory concentration.