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. 2019 Jun 25;55(2):451–461. doi: 10.3892/ijo.2019.4831

Figure 4.

Figure 4

miR-1 promoted the drug accumulation in multidrug resistant gastric cancer cells. (A) Flow cytometric analysis of the Rhodanmin123 accumulation in SGC7901/ADM and SGC7901/VCR cells with transfection of miR-NC, miR-1 mimics and miR-1 inhibitor. (B) The protein expression levels of MDR1/P-gp and MRP-1 in SGC7901/ADM and SGC7901/VCR cells with transfection of miR-NC, miR-1 mimics and miR-1 inhibitor. Data are presented as the mean ± standard deviation of three repeated experiments. *P<0.05. miR, microRNA; VCR, vincristine; ADM, adriamycin; miR-NC, scramble control; MDR1/P-gp, multidrug resistance protein 1/P-glycoprotein; MRP-1, multidrug resistance-associated protein 1.