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. 2019 Jun 25;55(2):451–461. doi: 10.3892/ijo.2019.4831

Figure 6.

Figure 6

Overexpression of sorcin partially recovered the effect of miR-1 on multidrug resistance in gastric cancer cells. (A) The expression level of sorcin in SGC7901/ADM and SGC7901/VCR cells with transfection of miR-NC, miR-1 mimics and miR-1 mimics with pcDNA-sorcin. (B) IC50 of ADM to SGC7901/ADM cells following transfection of miR-NC, miR-1 mimics and miR-1 mimics with pcDNA-sorcin. (C) IC50 of VCR to SGC7901/VCR cells following transfection of miR-NC, miR-1 mimics and miR-1 mimics with pcDNA-sorcin. Data are presented as the mean ± standard deviation of three repeated experiments. *P<0.05, **P<0.01. miR, microRNA; VCR, vincristine; ADM, adriamycin; IC50, half maximal inhibitory concentration; miR-NC, scramble control.