Table I.
UPN | FAB | Age | Sex | PBB (%) | WBC (g/l) | Hb (g/dl) | Plt (g/l) | Cytogenetics | Molecular markers | ELN cytogenetic risc group | NCCN cytogenetic risc group | AML blast characteristics |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | M5 | 81 | M | 60 | 61.3 | 11.7 | 72 | 46, XY | MLLT3/MLL t(9;11) n.d. CEBPA n.d., PML/RARA t(15;17) negative, RUNX1/RUNX1T1 t(8;21) negative, CBFB/MYH11 inv(16) negative, FLT3-ITD negative, FLT3-TKD wild-type, NPM1 mutation type A |
Favorable | Better-risk | CD33+ |
2 | M5 | 71 | F | 24 | 18.0 | 7.1 | 127 | 46, XX | MLLT3/MLL t(9;11) negative, CEBPA wild-type, PML/RARA t(15;17) negative, RUNX1/RUNX1T1 t(8;21) negative, CBFB/MYH11 inv(16) negative, FLT3-ITD negative, FLT3-TKD wild-type, NPM1 mutation type D |
Favorable | Better-risk | CD33+ |
AML, acute myeloid leukemia; UPN, uniform patient number; FAB, French-American-British classification; F female; M, male; PBB, peripheral blood blasts among nucleated cells; WBC, white blood count; Hb, hemoglobin; Plt, platelets; ELN, European LeukemiaNet; NCCN, National Comprehensive Cancer Network; n.d., not determined.