TABLE 2.

Duration of action, potency, and half-life

	Hydrochlorothiazide	Chlorthalidone	Indapamide SR
Half-life [46,47,48]	6–15 h	40–60 h	14–24 h
Duration of action [49,50]	16–24 h	48–72 h	>24
Equipotency for office SBP [51,52,53]	25 mg	12.5 mg	1.5 mg
Dose effect for office SBP [53,54]	Yes	Mixed data	No

SR, sustained release.