Figure 1:

Sequencing depth on chromosome X before and after XYalign. Mean sequencing depth for the Dataset 1 XX individual in 5-kb windows across the X chromosome before (A) and after (B) XYalign processing. Changes in depth (D) are presented as the sign of the difference times the absolute value of the log₁₀ difference, where the difference is depth after XYalign minus depth before XYalign. The chromosome map (C) presents the location of X chromosome genomic features depicted in the legend. X chromosome coordinates are identical in all plots.