All scaffolds display upregulated genes related to osteogenesis – COL1A2, BGLAP, BMP2, OSX, and RUNX2 – and more dynamic expression profiles of zinc transporters – ZNT7, ZIP1, and ZIP13. See Supplemental Figure 2 for long-term gene expression profiles. ^: significance at p<0.05 for indicated groups. ^: significance at p<0.05 compared to mineralized scaffold. **: significant at p<0.05 compared to all groups. N.S.: no significance between indicated groups. #: significant (p<0.05) decrease compared to Day 1 within experimental group. §: significant (p<0.05) increase compared to Day 1 within experimental group.