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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: J Mol Neurosci. 2019 May 10;68(4):603–619. doi: 10.1007/s12031-019-01321-z

Fig. 9.

Fig. 9

Multiple parameters of dorsal root ganglion cultures to demonstrate no significant toxicity after mNCX-1 siRNA treatment. In part A, a time course of Alamar Blue fluorescence response on day 9, which was 5 days after treatment with mNCX-1 siRNA. Control cultures (closed circles) are compared to response in mNCX-1 siRNA (open circles), indicating no significant difference between the groups at any time point from 1 to 5 hours (ANOVA). Each point is the mean of six determinations ± the standard error. In part B, high content image analyses of dorsal root ganglion were utilized to measure seven neuronal parameters. Control cultures were compared with cultures 5 days after treatment with mNCX-1 siRNA. Each value if the mean of 10 determinations from duplicate experiments ± the standard error. No statistically significant differences were observed between the two groups for any of the neuronal parameters.