Table 1. Description of the patient cohort, including gender, age, and general condition quantified by Karnofsky and Eastern Cooperative Oncology Group (ECOG) Score at time of initial diagnosis, tumor location, and size.
| Sex | Age (years) | Karnofsky score | Initial ECOG score | Tumor location | Tumor size (mm × mm × mm) | MGMT promotor methylation status | p53 accumulation | KI67Li | EGFR vIII | Survival (days) |
|---|---|---|---|---|---|---|---|---|---|---|
| m | 65 | 80 | 1 | Right temporal | 30 × 30 × 30 | Methylated | Sporadicly accumulated | >10% | n.a. | 189 |
| f | 51 | 70 | 1 | Left trigonal postcentral | 22 × 39 × 26 | Not methylated | Moderately accumulated | 5% | − | 446 |
| m | 71 | 80 | 1 | Right parietal | 43 × 46 × 48 | Methylated | Strongly accumulated | 50% | + | 533 |
| m | 69 | 80 | 1 | Left parietal | 30 × 30 × 30 | Not methylated | Sporadicly accumulated | 6% | − | 297 |
| m | 67 | 90 | 0 | Right frontal | 40 × 40 × 40 | Methylated | Strongly accumulated | 30% | − | 728 |
| f | 66 | 100 | 0 | Right temporal | 17 × 20 × 16 | Methylated | Moderately accumulated | 50% | − | 1278 |
| m | 63 | 80 | 1 | Right frontal | 20 × 22 × 20 | Not methylated | Focally accumulated | 30% | + | 724 |
| m | 53 | 90 | 0 | Left occipitomesial | 17 × 28 × 18 | Not methylated | Strongly accumulated | 10% | + | 512 |
| m | 73 | 90 | 0 | Right trigonal | 47 × 47 × 38 | Methylated | Weakly accumulated | 20% | − | 503 |
| m | 59 | 80 | 1 | Right temporal | 23 × 33 × 33 | Methylated | Strongly accumulated | 20% | − | 562 |
| m | 61 | 70 | 1 | Left parietal | 40 × 40 × 40 | Methylated | Focally accumulated | 20% | − | 361 |
| m | 67 | 80 | 1 | Left frontolateral | 20 × 30 × 30 | Methylated | Moderately accumulated | 30% | − | 225 |
| m | 46 | 100 | 0 | Left central | 31 × 45 × 42 | Methylated | Moderately accumulated | 30% | + | 857 |
| m | 57 | 90 | 0 | Left temporal | 39 × 35 × 17 | Methylated | Weakly accumulated | 10% | − | 834 |
| m | 72 | 90 | 0 | Left temporal | 17 × 39 × 19 | Methylated | Strongly accumulated | 20% | + | 661 |
| m | 66 | 90 | 0 | Left temporal | 37 × 50 × 44 | Not methylated | Strongly accumulated | 20% | − | 649 |
| m | 45 | 80 | 1 | Left temporal | 31 × 28 × 35 | Not methylated | Sporadicly accumulated | 30% | − | 577 |
| m | 72 | 90 | 0 | Left temporal | 30 × 40 × 43 | Not methylated | Moderately accumulated | Up to 50% | − | 387 |
| m | 40 | 90 | 0 | Left temporal | 28 × 34 × 31 | Not methylated | Weakly accumulated | 30% | − | 544 |
| f | 70 | 90 | 0 | Right postcentral | 22 × 35 × 27 | Methylated | Moderately accumulated | Up to 20% | − | 328 |
All patients showed expression of wildtype isocitrate dehydrogenase (IDH), further parameters such as promotor methylation status of the O6-methylguanine-DNA-methyltransferase (MGMT), p53 accumulation, Ki67 Labeling index (Ki67Li), and expression of epidermal growth factor receptor (EGFR) variant III are listed above as well as survival time as days between initial diagnosis and death.