Table 2.
Characteristics | Univariate | Multivariate | ||||
---|---|---|---|---|---|---|
HR | 95%CI | p-value | HR | 95%CI | p-value | |
Age (years) | 1.039 | 1.028–1.051 | < 0.001* | 1.039 | 1.028–1.051 | < 0.001* |
Sex | < 0.001* | 0.001* | ||||
Male | Reference | Reference | ||||
Female | 0.671 | 0.554–0.813 | < 0.001* | 0.711 | 0.584–0.867 | 0.001* |
Laterality | 0.553 | |||||
Left | Reference | |||||
Right | 0.944 | 0.780–1.142 | 0.553 | |||
Race | 0.438 | |||||
White | Reference | |||||
Black | 1.128 | 0.811–1.570 | 0.473 | |||
Other | 0.685 | 0.409–1.149 | 0.151 | |||
Unknown | 0.002 | 0–791532416 | 0.947 | |||
Marital status | 0.028* | 0.047* | ||||
Married | Reference | Reference | ||||
Unmarried | 1.254 | 1.033–1.522 | 0.022 | 1.264 | 1.036–1.543 | 0.021* |
Unknown | 0.725 | 0.385–1.366 | 0.320 | 0.830 | 0.439–1.568 | 0.565 |
Year at diagnosisa | 0.179 | |||||
Statea | 0.173 | |||||
Surgical lobe | 0.697 | |||||
Upper | Reference | |||||
Middle | 1.116 | 0.527–2.363 | 0.775 | |||
Lower | 0.894 | 0.729–1.096 | 0.280 | |||
Unknown | 1.239 | 0.307–4.994 | 0.763 | |||
Surgery | 0.005* | 0.009* | ||||
Wedge | Reference | Reference | ||||
Segmentectomy | 0.759 | 0.626–0.920 | 0.005* | 0.774 | 0.638–0.939 | 0.009* |
Grade | < 0.001* | < 0.001* | ||||
I | Reference | Reference | ||||
II | 2.041 | 1.533–2.716 | < 0.001* | 1.874 | 1.405–2.500 | < 0.001* |
III | 2.414 | 1.761–3.308 | < 0.001* | 2.448 | 1.776–3.375 | < 0.001* |
IV | 2.188 | 0.686–6.981 | 0.186 | 2.234 | 0.696–7.166 | 0.177 |
Unknown | 1.422 | 0.839–2.412 | 0.191 | 1.611 | 0.946–2.743 | 0.079 |
Stage | < 0.001* | 0.004* | ||||
IA1 | Reference | |||||
IA2 | 1.738 | 1.247–2.423 | 0.001* | 1.454 | 1.040–2.033 | 0.029* |
IA3 | 2.316 | 1.639–3.272 | < 0.001* | 1.757 | 1.237–2.496 | 0.002* |
HR, hazard ratio; CI, confidence interval.
Detailed data of year at diagnosis and state are listed in Table S2.
Indicates p < 0.05.