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. 2019 Jul 3;13:687. doi: 10.3389/fnins.2019.00687

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Copyright © 2019 Darwish, Chamaa, Al-Chaer, Saadé and Abou-Kheir.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transient reduction of TH positive neurons in the injected substantia nigra. (A) Tile scans of the injected (right) and non-injected (left) SN stained for TH in sham and ET injected rats showing a decrease in the number of TH-ir cells in the injected side of SN at day 3 only. (B) Bar charts representing the percent variations of TH positive cells count in sham (n = 5) and ET-injected rats at different time intervals (n = 5 at each time point). A significant decrease is noted at day 3 (P < 0.001) post-injection. Student t-test was used to determine statistical significance.