Table 2.
Summary of all combinations of MRI sequences with histological or physical technique.
| MRI | Histological or physical technique | References |
|---|---|---|
| T1 or T1 map | Perls | Matsuda et al., 2017, Lee et al., 2018 |
| T1 PSIR | Perls + DAB | Wallace et al., 2016 |
| T1 PSIR | Turnbull + DAB | Wallace et al., 2016 |
| T2 or T2map | Perls | Chen et al., 1989, Fujii et al., 2007, Tatsumi et al., 2008, Matsusue et al., 2008, De Reuck et al., 2011, Massey et al., 2012, Liem et al., 2012, Foroutan et al., 2013, van Veluw et al., 2016, Massey et al., 2017, Matsuda et al., 2017, Lee et al., 2018 |
| T2 or T2 map | AAS | Chen et al., 1989 |
| T2 or T2map | Radio-immune assay kit and peroxidase-antiperoxidase method | Chen et al., 1989 |
| T2 or T2 map | IHC: Ferritin | Fujii et al., 2007, Matsusue et al., 2008, Matsusue et al., 2009, Foroutan et al., 2013 |
| T2* or T2* map | Perls | Tatsumi et al., 2008, De Reuck et al., 2011, Liem et al., 2012, Blazejewska et al., 2013, Foroutan et al., 2013, Lee et al., 2016, van Veluw et al., 2016, De Reuck et al., 2017, Matsuda et al., 2017, Lee et al., 2018 |
| T2* or T2* map | Perls + DAB | Dhenain et al., 2002, van Rooden et al., 2009, Meadowcroft et al., 2015, Bulk et al., 2018b |
| T2* or T2* map | IHC: Ferritin | Foroutan et al., 2013, Dusek et al., 2016 |
| T2* or T2* map | Turnbull + DAB + Ammonium sulfide | Dusek et al., 2016 |
| T2* or T2* map | XRF | Zheng et al., 2012 |
| T2* or T2* map | AAS | Dusek et al., 2016 |
| R1 | Perls | House et al., 2008, Stüber et al., 2014 |
| R1 | ICP-AES | House et al., 2008 |
| R1 | PIXE | Stüber et al., 2014 |
| R2 | Perls | House et al., 2008, Walsh et al., 2013 |
| R2 | AAS | House et al., 2007 |
| R2 | ICP-AES | House et al., 2008 |
| R2 | ICP-MS | Langkammer et al., 2010, Langkammer et al., 2012 |
| R2 | XRF | Antharam et al., 2012 |
| R2' and TcR2' | ICP-MS | Birkl et al., 2015 |
| R2' and TcR2' | SQUID | Birkl et al., 2015 |
| R2* | Perls | Walsh et al., 2013, Stüber et al., 2014, Wisnieff et al., 2015 |
| R2* | Perls + DAB | Fukunaga et al., 2010, Bagnato et al., 2011, Kwan et al., 2012, Meadowcroft et al., 2015, Wallace et al., 2016 |
| R2* | Turnbull + DAB | Wallace et al., 2016 |
| R2* | Turnbull + DAB + Ammonium sulfide | Bagnato et al., 2011, Dusek et al., 2016, Bagnato et al., 2018, Hametner et al., 2018, |
| R2* | Ferritin : IHC | Fukunaga et al., 2010, Bagnato et al., 2011, Kwan et al., 2012, Dusek et al., 2016, Birkl et al., 2017 |
| R2* | Ferrozine assay | Hametner et al., 2018 |
| R2* | ICP-MS and LA-ICP-MS | Yao et al., 2009, Langkammer et al., 2010, Langkammer et al., 2012, Wisnieff et al., 2015 |
| R2* | PIXE | Stüber et al., 2014 |
| R2* | XRF | Antharam et al., 2012 |
| R2* | AAS | Dusek et al., 2016 |
| R2* | EPR | Bulk et al., 2018a |
| R2* | SQUID | Bulk et al., 2018a |
| TcR2* | IHC : Ferritin | Birkl et al., 2017 |
| SWI | Perls | Lee et al., 2018 |
| SWI | Perls + DAB | Schrag et al., 2010b |
| SWI | Turnbull + DAB | Dal-Bianco et al., 2017 |
| SWI | XRF | Hopp et al., 2010, Zheng et al., 2012 |
| Phase | Perls | Walsh et al., 2013 |
| Phase | Perls + DAB | Bagnato et al., 2011 |
| Phase | Turnbull + DAB + Ammonium sulfide | Bagnato et al., 2011 |
| Phase | IHC: Ferritin | Bagnato et al., 2011 |
| Phase | ICP-MS | Langkammer et al., 2012 |
| Phase | XRF | Hopp et al., 2010 |
| QSM | Perls | Stüber et al., 2014, Sun et al., 2015, Wisnieff et al., 2015, Lee et al., 2018 |
| QSM | Perls + DAB | Kaunzner et al., 2019 |
| QSM | Turnbull + DAB + Ammonium sulfide | Wiggermann et al., 2017, Hametner et al., 2018 |
| QSM | ICP-MS and LA-ICP-MS | Langkammer, 2012, Tan et al., 2014, Wisnieff et al., 2015 |
| QSM | XRF | Zheng et al., 2013 |
| QSM | Ferrozine assay | Hametner et al., 2018 |
AAS, atomic absorption spectrometry; CAA, cerebral amyloid angiopathy; DAB, diaminobenzidine; EPR, electron paramagnetic resonance; ICP-AES, inductively coupled plasma atomic emission spectrometry; ICP-MS, inductively coupled plasma mass spectrometry; IHC, immunohistochemistry LA-ICP-MS, laser ablation ICP-MS; MSA, multiple system atrophy; PIXE, particle induced X-ray emission; PSIR, T1 phase sensitive inversion recovery; QSM, quantitative susceptibility mapping; SQUID, superconducting quantum interference device magnetometer; SWI, susceptibility weighted images; TcR2*, temperature coefficient R2*; XRF, X-ray fluorescence. Quantitative correlations are indicated in bold.