Table 2.

Significant patterns in 3′ UTR poly(A) sites.

Hexamer	Observed1	Expected2	Coverage3	Position4	P5	Location6
AAUAAA	6,609	1,303	47.7%	−23 ± 4.1	0
AUUAAA	2,347	419	26.2%	−23 ± 4.3	0
UAUAAA	852	226	21.5%	−24 ± 4.9	0
AGUAAA	485	112	11.3%	−23 ± 4.6	2 × 10−280
AUAUAU	465	96	20.1%	−23 ± 6.2	1 × 10−277
AAUACA	393	81	13.5%	−23 ± 5.1	2 × 10−270
AAAAAA	1,111	359	19.5%	−23 ± 6.0	6 × 10−181
CAUAAA	342	77	10.8%	−24 ± 5.0	3 × 10−205
GAUAAA	228	57	8.0%	−24 ± 4.8	3 × 10−113
AAUAUA	192	67	19.9%	−23 ± 5.4	1 × 10−53
AAUGAA	200	73	15.2%	−23 ± 6.0	8 × 10−51
ACUAAA	151	51	8.6%	−24 ± 5.8	2 × 10−45

¹The occurrence of hexamer in PE region of all poly(A) sites.

²The expected occurrences based on the first-order Markov chain model in PE region of all poly(A) sites.

³Coverage of hexamers in the PE region of all poly(A) sites.

⁴A position is denoted by average ± SD. The mean position of each pattern in the PE region and the standard deviation (SD) were used as a measure of scattering.

⁵The probability of reaching the observed frequency by chance based on a cumulative binomial distribution.

⁶Distribution of hexamers in the PE region.