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. 2019 Jul 3;10:613. doi: 10.3389/fgene.2019.00613

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Copyright © 2019 Ramos-Molina, Sánchez-Alcoholado, Cabrera-Mulero, Lopez-Dominguez, Carmona-Saez, Garcia-Fuentes, Moreno-Indias and Tinahones

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Association between the DNA methylation status of insulin like growth factor 2 mRNA binding protein 2 (IGF2BP2) and the gut microbiota composition in obese subjects. (A) Methylation of IGF2BP2 (쌠β value) in the HighBFR vs. LowBFR groups in both visceral adipose tissue and whole blood. Data (n = 10 per group) are plotted as means ± SE. Significance was tested using Mann–Whitney U test and is indicated as *p < 0.05. (B) Spearman correlations between IGF2BP2 methylation in visceral adipose tissue and the ratio Bact/Firm or the relative abundance (%) of Bacteroidetes.