Table 1.
Parameter | Subjects in the Janssen study [18] | Lung-cancer patients administered VAL401 in the present study | |||||
---|---|---|---|---|---|---|---|
Young (count and mean ± SD) | Elderly (count and mean ± SD) | Liver disease (count and mean ± SD) | Moderate renal disease (count and mean ± SD) | Severe renal disease (count and mean ± SD) | All patients (count and mean) | ||
No. of subjects | 8 | 12 | 8 | 7 | 7 | 42 | 8 |
Gender | |||||||
Male | 5 | 7 | 3 | 3 | 4 | 22 | 5 |
Female | 3 | 5 | 5 | 4 | 3 | 20 | 3 |
Age (years) | 30 ± 4 | 69 ± 4 | 51 ± 12 | 56 ± 13 | 52 ± 13 | 52 | 65.8 ± 9 |
Age range (years) | 25–35 | 65–78 | 35–73 | 34–68 | 29–66 | 38–64 | 54–76 |
Weight (kg) | 78 ± 19 | 78 ± 16 | 85 ± 17 | 82 ± 18 | 78 ± 20 | 80 | 68.3 ± 9 |
Height (cm) | 172 ± 15 | 169 ± 10 | 166 ± 11 | 170 ± 15 | 174 ± 9 | 170 | 169 ± 7 |