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. 2019 Jan 9;44(4):557–565. doi: 10.1007/s13318-018-00538-4

Table 1.

Summary of demographic information for the subjects in the Janssen study [18] and the patients in the VAL401 study

Parameter Subjects in the Janssen study [18] Lung-cancer patients administered VAL401 in the present study
Young (count and mean ± SD) Elderly (count and mean ± SD) Liver disease (count and mean ± SD) Moderate renal disease (count and mean ± SD) Severe renal disease (count and mean ± SD) All patients (count and mean)
No. of subjects 8 12 8 7 7 42 8
Gender
 Male 5 7 3 3 4 22 5
 Female 3 5 5 4 3 20 3
Age (years) 30 ± 4 69 ± 4 51 ± 12 56 ± 13 52 ± 13 52 65.8 ± 9
Age range (years) 25–35 65–78 35–73 34–68 29–66 38–64 54–76
Weight (kg) 78 ± 19 78 ± 16 85 ± 17 82 ± 18 78 ± 20 80 68.3 ± 9
Height (cm) 172 ± 15 169 ± 10 166 ± 11 170 ± 15 174 ± 9 170 169 ± 7