Table 3.

Multivariate analysis of outcomes based on patient, disease, and transplant characteristics

	RI		NRM		LFS		OS		GRFS		aGVHD grade II-IV		cGVHD
	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
ATG vs no ATG	1.45 (0.90-2.34)	.13	0.54 (0.32-0.91)	.02	0.90 (0.65-1.25)	.53	0.85 (0.61-1.20)	.36	0.8 (0.60-1.07)	.13	0.28 (0.18-0.44)	<.01	0.63 (0.42-0.94)	.02
Age (per 10 y)	1.11 (0.97-1.27)	.13	1.18 (0.98-1.41)	.08	1.13 (1.01-1.25)	.03	1.13 (1.01-1.27)	.03	1.08 (0.99-1.19)	.09	0.89 (0.77-1.03)	.13	1.14 (1.01-1.28)	.03
Disease status at allo-HCT
Advanced vs CR1	2.47 (1.68-3.63)	<.01	1.09 (0.59-2.04)	.78	1.88 (1.37-2.58)	<.01	1.81 (1.3-2.51)	<.01	1.67 (1.25-2.23)	<.01	1.6 (1.04-2.45)	.03	1.15 (0.74-1.78)	.54
Cytogenetics
Poor vs favorable	2.84 (1.67-4.83)	<.01	1.45 (0.76-2.76)	.26	2.22 (1.5-3.29)	<.01	2.31 (1.52-3.49)	<.01	1.52 (1.09-2.11)	.01	0.99 (0.58-1.7)	.98	0.67 (0.42-1.06)	.08
KPS
≥90% vs <90%	0.80 (0.55-1.16)	.24	0.53 (0.34-0.83)	<.01	0.70 (0.54-0.92)	.01	0.64 (0.49-0.85)	<.01	0.80 (0.63-1.02)	.07	0.81 (0.56-1.19)	.29	1.09 (0.78-1.52)	.62
Donor type
UD 10/10 vs MSD	0.72 (0.45-1.15)	.17	2.79 (1.64-4.73)	<.01	1.24 (0.89-1.73)	.20	1.39 (0.99-1.96)	.06	1.14 (0.85-1.53)	.39	3.33 (2.19-5.05)	<.01	1.29 (0.88-1.89)	.19
UD 9/10 vs MSD	0.67 (0.36-1.25)	.21	3.02 (1.57-5.82)	<.01	1.24 (0.81-1.91)	.33	1.38 (0.88-2.16)	.16	1.49 (1.02-2.17)	.04	3.09 (1.72-5.53)	<.01	1.52 (0.93-2.5)	.10
Graft source
PB vs BM	1.62 (1.02-2.58)	.04	1.08 (0.65-1.81)	.76	1.39 (1.01-1.93)	.04	1.44 (1.02-2.03)	.04	1.33 (1.01-1.74)	.04	0.99 (0.64-1.52)	.95	1.01 (0.71-1.43)	.97