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. 2019 Jun 27;3(13):1930–1938. doi: 10.1182/bloodadvances.2018028530

Table 2.

Subgroup analysis for OS from diagnosis in patients with acquired del(17p) and controls based on prognostic factors at diagnosis and therapy

Subgroup No. of patients with available data in the subgroups Acquired del(17p) (n = 76) Controls (n = 152) P*
Age, y
 <65 48 vs 101 72.3 (49.6-99.0) 106.1 (98.5-127.8) .002
 ≥65 28 vs 51 58.2 (44.1-71.3) 105.9 (68.6-138.8) <.001
Translocation
 High risk 14 vs 14 56.8 (24.0-119.0) 98.3 (60.5-111.8) .419
 No high risk 62 vs 138 68.9 (50.8-74.8) 111.7 (103.4-129.3) <.001
ISS
 I/II 42 vs 110 71.3 (50.8-75.4) 106.1 (101.6-129.3) <.001
 III 14 vs 26 44.4 (13.8-103.1) 104.8 (60.7-111.8) .036
LDH
 Low 44 vs 116 63.8 (44.6-99.0) 105.9 (98.5-119.4) .004
 High 7 vs 5 55.5 (23.2-86.4) 100.9 (80.6-NR) .011
PC proliferative rate
 Low 31 vs 84 74.6 (58.3-99.0) 106.1 (98.3-137.8) .025
 High 14 vs 24 42.2 (24.0-103.1) 103.4 (67.1-NR) .031
PI-containing induction 21 vs 37 34.5 (24.0-50.8) 104.8 (70.2-137.8) <.001
Others 55 vs 115 74.6 (63.8-96.5) 106.1 (98.5-127.8) .003

NR, not reached.

*

P for log-rank test for Kaplan-Meier analysis.