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. 2019 Jul 10;39(28):5534–5550. doi: 10.1523/JNEUROSCI.1451-18.2019

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Figure 4. — Healthy elderly show cross-sectional and longitudinal changes in mean participation coefficient and system segregation. A, B, Bar charts indicate mean (±2 SE) participation coefficient and system segregation of young and elderly participants at baseline. *indicates a statistically significant difference (p < 0.05) between young and elderly participants at baseline. C, D, Spaghetti plots indicate model-fitted longitudinal changes in mean participation coefficient and system segregation for each individual. Results displayed are thresholded at p < 0.05. Healthy elderly showed higher mean participation coefficient across all nodes and lower global system segregation compared with young participants as well as with time.