Table 2.
Genes up and down-regulated in WT during co-culture with B. fragilis relative to the WT C. difficile monoculture.
| No | Gene ID | log2FoldChange | Gene Annotation |
|---|---|---|---|
| 1 | CDR20291_0194 | 1.3822081 | 10 kDa chaperonin |
| 2 | CDR20291_1016 | 1.7087847 | glycerol-3-phosphate acyltransferase PlsX |
| 3 | CDR20291_1017 | 1.7011992 | 3-oxoacyl-ACP synthase III |
| 4 | CDR20291_1018 | 1.2469326 | trans-2-enoyl-ACP reductase |
| 5 | CDR20291_1337 | 1.3290499 | transcriptional regulator |
| 6 | CDR20291_1861 | 1.412304 | biotin carboxylase acetyl-CoA carboxylase subunit A |
| 7 | CDR20291_2027 | 1.6309458 | 2-nitropropane dioxygenase |
| 8 | CDR20291_3225 | 1.0229025 | formate/nitrite transporter |
| 9 | CDR20291_0363 | −1.377088 | radical SAM protein |
| 10 | CDR20291_0364 | −1.003595 | hypothetical protein |
| 11 | CDR20291_0365 | −1.461207 | (R)-2-hydroxyisocaproate dehydrogenase |
| 12 | CDR20291_0659 | −1.248536 | radical SAM protein |
| 13 | CDR20291_1271 | −1.15672 | hypothetical protein |
| 14 | CDR20291_1309 | −1.208811 | phosphohydrolase |
| 15 | CDR20291_1400 | −1.833327 | imidazole glycerol phosphate synthase subunit HisH |
| 16 | CDR20291_1834 | −1.411634 | ethanolamine/propanediol ammonia-lyase heavy chain |
| 17 | CDR20291_2416 | −1.231651 | hypothetical protein |
| 18 | CDR20291_2417 | −1.574982 | hypothetical protein |
| 19 | CDR20291_2610 | −1.046807 | two-component sensor histidine kinase |
Note: P-adjusted value ≤ 0.05.